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Majorproblem
Joined: 15 Mar 2011
Posts: 1
Location: Midwest
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 Posted: March 16 2011 Post subject: Lunesta and Trazadone |
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Hello,
I am new to boards, but wish I could have found it years ago. I have suffered from insomnia for too many years to count. I am so glad to have found all of you.
My question for anyone is if they know if it is safe to take Lunesta 3mg and Trazadone 50mg for sleep. I take also Lexapro for depression and anxiety. I appreciate any help.
Thanks, Majorproblem |
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mosspa
Joined: 16 Mar 2006
Posts: 489
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| Posted: July 20 2011 Post subject: |
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| Yes, butr I would gradually ween yourself off the Lunesta and increase the Trazodone up to 100mg. Technically, from a 'death' perspective nothing you mix with Lunesta is particularly dangerous because it doesn't affect the systems responsible for breathing (e.g., you could dring a half a bottle of scotch, rake 5 lunesta, pass out for about 16 hours and be fine afterward). Trazodone has a bit mot interactions woit other drugs, but the main point is that you should get off Lunesta as quickly as possibly and stay off. Drinking a bottle of wine before bedtime is much better than taking Lunesta if you can deal with the caloric challenge. |
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heapsreal
Joined: 26 Apr 2010
Posts: 35
Location: australia, brisbane
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| Posted: July 20 2011 Post subject: |
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Can i ask why your not keen on lunesta, it is similar to zopiclone from memory and it has been my most reliable med i have used for sleep. Do you have this view of all the z-drugs?
cheers!!! |
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mosspa
Joined: 16 Mar 2006
Posts: 489
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| Posted: September 14 2012 Post subject: |
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| heapsreal wrote: | Can i ask why your not keen on lunesta, it is similar to zopiclone from memory and it has been my most reliable med i have used for sleep. Do you have this view of all the z-drugs?
cheers!!! |
Over a year later.... yes I'm not too keen on any z-drugs or benzos for chronic use for sleep. The only rational sleep drug is Xyrem (sodium oxybate). If you are a normal sleeper that is undergoing a bout of insomnia than the z-drugs or benzos are fine. The problem with chronic use of z-drugs or benzos is down regulation of receptors in the GABA-a complex. This receptor reconfiguration only makes insomnia worse in the long run. Xyrem is a GABA-b drug. The other safe drugs to use are ethanol (alcohol) and chloral hydrate. I've been an on-and-off insomniac for over 40 years. Unless you are willing to use GHB (Xyrem) there really is no sensible solution from a pharmacological perspective.
Moss |
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susanmh
Joined: 20 Aug 2006
Posts: 8
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| Posted: September 14 2012 Post subject: |
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Lunesta never worked for me nor did Trazadone. But trazadone helps my husband. Altho he is not a hard core insomniac.
Neurontin has worked for me and so has a low dose of Ambien. The trick with Ambien is to realize you will still have a night or two where you don't sleep but don't up your dosage, try to keep it at 5mg or even less. Ambien actually works better the less you take. Neurontin is good especially if you also have RLS/PLM. It is sedating and non addictive.
Non of the non-med treatments have worked for me. But different things work for different people. Try meditation, self-hypnosis, good sleep hygiene and see if it helps.
Good luck! |
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heapsreal
Joined: 26 Apr 2010
Posts: 35
Location: australia, brisbane
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| Posted: October 03 2012 Post subject: |
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| susanmh wrote: | Lunesta never worked for me nor did Trazadone. But trazadone helps my husband. Altho he is not a hard core insomniac.
Neurontin has worked for me and so has a low dose of Ambien. The trick with Ambien is to realize you will still have a night or two where you don't sleep but don't up your dosage, try to keep it at 5mg or even less. Ambien actually works better the less you take. Neurontin is good especially if you also have RLS/PLM. It is sedating and non addictive.
Non of the non-med treatments have worked for me. But different things work for different people. Try meditation, self-hypnosis, good sleep hygiene and see if it helps.
Good luck! |
Hi Mosspa, whats your opinion on helping reverse benzo tolerence with nmda antagonists such as dextromethorphan(dxm) or maybe delaying benzo tolerence.
I have found benzo holidays and alternating sleep meds has helped me keep my doses down and i have had some success with DXM. DXM did seem to help me when i took a fortnight off all benzo's and just used antihistiamines etc for sleep. Possibly made benzo withdrawal more tolerable maybe??
cheers!!! |
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Rosbergs3
Joined: 14 Mar 2008
Posts: 69
Location: Atlanta
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| Posted: October 20 2012 Post subject: |
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| I cant stand Trazadone. It makes me feel like lead or cement the next morning. |
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mosspa
Joined: 16 Mar 2006
Posts: 489
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| Posted: January 17 2013 Post subject: |
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[quote=Hi Mosspa, whats your opinion on helping reverse benzo tolerence with nmda antagonists such as dextromethorphan(dxm) or maybe delaying benzo tolerence.
I have found benzo holidays and alternating sleep meds has helped me keep my doses down and i have had some success with DXM. DXM did seem to help me when i took a fortnight off all benzo's and just used antihistiamines etc for sleep. Possibly made benzo withdrawal more tolerable maybe??
cheers!!![/quote]
I never thought of that. Actually, I didn't even know that DXM was an NMDA antagonist until I looked it up. I've never used it as such in an experimental situation. But, yes, it should work at some level. Notice that Ph.D. in neuropsychopharmacology doesn't equal omniscient  |
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