Narcolepsy is a chronic sleep disorder with no known cause. The main characteristic of narcolepsy is excessive and overwhelming daytime sleepiness, even after adequate nighttime sleep. A person with narcolepsy is likely to become drowsy or to fall asleep, often at inappropriate times and places.
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Sodium Oxybate (Xyrem), the most recently approved new medication for patients with narcolepsy was approved for the treatment of cataplexy in July of 2002. Recent clinical trials have also demonstrated Xyrem's effectiveness in treating the symptom of daytime sleepiness. A supplemental new drug application will be filed with the FDA to gain approval for this indication as well.
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