Merck’s Phase III trials for suvorexant, an investigational medicine for the treatment of insomnia, determined that suvorexant’s 15 mg and 20 mg doses were effective and generally well-tolerated over 3 months in adult patients with insomnia. The data was presented at the SLEEP show.
Based on the analysis, the product reduced how long it took patients to fall asleep while increasing how long it took patients to stay asleep, as early as the first night and at 3 months compared to placebo.
Suvorexant targets insomnia in a way that is different from current treatments, the company says. The investigational medicine targets and inhibits the actions of orexins, neurotransmitters in a specific part of the brain that play a role in keeping a person awake.
– See more at: http://www.sleepreviewmag.com/2014/06/investigational-medicine-suvorexant-effective-well-tolerated-insomnia/#sthash.q8CTE1eD.dpuf
Originally posted in Sleep ReviewRead More
Large pharmaceutical companies have poured untold millions into developing and marketing Insomnia drugs, and their drive to find the magic pill has largely paid off.
Big pharma R&D teams know what virtually everyone knows instinctively: good sleep is hard to come by, and insomnia can be a maddening affliction. For those who don’t want to ingest drugs (or pay for them), some simple, time-tested tips can boost the odds for sound sleep.
Number one on the list is exercise. Numerous studies confirm that consistent strenuous aerobic activity tires you out in a way that establishes restful sleep patterns that your body will replicate night after night.
Do not do the exercise—whether it be walking, jogging, or elliptical—shortly before going to bed. That will raise the heart rate and boost the stress hormones. Mid day or morning is best. Your body will remember, and your biological clock will fall into sync.
Number two on the anti-insomnia list is to pay attention to the bedroom environment.Read More