One study shows that in obese patients with moderate to severe sleep apnea, weight loss is the most important intervention and reduces inflammation, insulin resistance, dyslipidemia, and blood pressure. But CPAP had a meaningful incremental effect on blood pressure in fully adherent patients when used in addition to weight loss.
The second study provides more evidence that CPAP is effective for lowering blood pressure in patients with moderate to severe sleep apnea, even those with blood pressures in the normal range. But the study found no evidence of benefit of nocturnal oxygen supplementation on blood pressure in these patients.
Both studies are published in the June 12 issue of theNew England Journal of Medicine.